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A gene mutation is defined as change in the


A) structure of ribosomes.
B) nucleotide sequence of DNA.
C) activation of a gene.
D) nucleotide sequence of RNA.

E) C) and D)
F) A) and B)

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In the intestinal bacteria Escherichia coli, the DNA segment that contains the coding for the enzymes of lactose metabolism is called the lactose _________.

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What kind of mutation occurs when one base is changed to another at a single location in the DNA?


A) Deletion
B) Substitution
C) Neutral
D) Insertion

E) None of the above
F) B) and C)

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Which of the following contains four types of nucleotides but no uracil?


A) Ribosomal RNA
B) DNA
C) Messenger RNA
D) Transfer RNA
E) RNA polymerase

F) B) and E)
G) D) and E)

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Suppose the template DNA strand of a ʺmini-geneʺ has the base sequence TACCCGGATTCA. The anticodon of the tRNA that carries the first amino acid to the ribosome will be


A) AGU.
B) UAG.
C) UCA.
D) AUG.
E) UAC.

F) A) and C)
G) A) and B)

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Determine the sequence of bases in mRNA if the original DNA base sequence is TAGGCTAA.

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Imagine that the short DNA base sequence GGCTGC is transcribed and then translated by a ribosome. The following activated tRNA molecules are available in the cytoplasm: Imagine that the short DNA base sequence GGCTGC is transcribed and then translated by a ribosome. The following activated tRNA molecules are available in the cytoplasm:   What resulting dipeptide will form? A)  Glycine-cysteine B)  Proline-threonine C)  Cysteine-alanine D)  Threonine-glycine E)  Alanine-alanine What resulting dipeptide will form?


A) Glycine-cysteine
B) Proline-threonine
C) Cysteine-alanine
D) Threonine-glycine
E) Alanine-alanine

F) C) and D)
G) None of the above

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Which of the following has anticodons?


A) DNA
B) Messenger RNA
C) RNA polymerase
D) Transfer RNA
E) Ribosomal RNA

F) All of the above
G) A) and B)

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Which of the following contains codons?


A) Messenger RNA
B) Transfer RNA
C) DNA
D) Ribosomal RNA
E) RNA polymerase

F) A) and E)
G) C) and D)

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A gene can be mutated with no resulting functional change in the protein that is produced from that gene if


A) an entire codon has been removed.
B) RNA polymerase can edit the mutation from the mRNA produced during translation.
C) a codon has changed, but it codes for the same amino acid as the original codon.
D) the mutation alters the active site of an enzyme.

E) A) and D)
F) A) and C)

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How can a single gene code for more than one protein?


A) Different types of ribosomes translate the resulting mRNA, producing different proteins.
B) The exons within an mRNA can be spliced together in different ways.
C) Different RNA polymerases transcribe it and produce different proteins.
D) Different amino acid chains can be coded by the same mRNA.

E) A) and D)
F) B) and C)

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A mutation that results in a change in the codon-reading pattern could result from


A) a base substitution only.
B) either an insertion or a deletion of a base.
C) a base insertion only.
D) a base deletion only.

E) A) and B)
F) B) and C)

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Which of the following molecules function to transfer genetic information from one generation to the next?


A) mRNA
B) Protein molecules
C) DNA
D) Lipid molecules
E) tRNA

F) All of the above
G) A) and B)

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The process of converting the ʺmessageʺ of mRNA into a sequence of amino acids is called


A) translation.
B) transcription.
C) replication.
D) repression.
E) activation.

F) All of the above
G) A) and D)

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The sequence of nitrogen-containing bases on one strand of DNA could determine all of the following EXCEPT the sequence of


A) nitrogen-containing bases in mRNA.
B) nitrogen-containing bases in the other DNA strand.
C) ribose and phosphate molecules in tRNA.
D) amino acids in a protein molecule.

E) All of the above
F) C) and D)

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How can RNA be distinguished from DNA?


A) RNA does not contain a sugar.
B) RNA is single-stranded.
C) RNA is never found in the nucleus.
D) RNA lacks the base uracil.

E) A) and B)
F) B) and D)

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What is the site of protein synthesis in the cell?


A) Smooth endoplasmic reticulum
B) Nucleus
C) Ribosome
D) Nucleolus
E) Eukaryotic chromosome

F) C) and E)
G) A) and C)

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The type of RNA that binds to a specific amino acid is


A) nuclear RNA.
B) messenger RNA.
C) transfer RNA.
D) ribosomal RNA.

E) A) and D)
F) A) and C)

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Suppose one strand of a ʺmini-geneʺ has the base sequence TACCCGGATTCA. The last codon in the mRNA sequence will be


A) AGU.
B) TCA.
C) AGT.
D) UGA.

E) A) and C)
F) B) and D)

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The nitrogenous base uracil pairs with


A) cytosine.
B) thymine.
C) adenine.
D) uracil.
E) guanine.

F) D) and E)
G) B) and E)

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